Assistant
Professor of Chemistry, Saint Louis University (2004-present)
Education
Allegheny
College, B.S. in Chemistry, 1999
University of Rochester, M.S. in Chemistry, 2001
University of Rochester, Ph.D. in Chemistry (Biophysical),
2004
Research
My
research involves the study of RNA structural motifs in short,
synthetic RNA oligonucleotides. RNA samples are synthesized
synthetically and are then deprotected, purified, and annealed.
RNA thermodynamics (change in free energy, enthalpy, and entropy)
are derived from optical melting data collected using UV spectroscopy.
Three-dimensional structure and dynamics are investigated
by 1D and 2D nuclear magnetic resonance (NMR). RNA motifs
of interest include those motifs that occur most frequently
in nature and those containing base or backbone modifications.
Visit the Znosko Lab Website here.
