My
group's research involves the use of microchip-based analytical
devices to study various biological systems. Students in my
group receive a broad base of training in analytical chemistry
as well as biology and engineering. We use flow-based analysis,
capillary electrophoresis, electrochemistry and fluorescence
to probe and monitor various biological systems. Current projects
include: 1) the development of a microchip-based blood brain
barrier (BBB) mimic to study the effect of nitric oxide (NO)
on the integrity of the BBB (in collaboration with Dr. Dana
Spence, Wayne State University and supported by a grant from
the NIH); 2) development of a microchip-based analysis system/reactor
system to study the effect of NO on the onset of Parkinson's
disease (supported by a grant from the NIH); 3) development
of novel sensitive and selective methods for monitoring endogenous
thiols; and 4) development of chip-based immobilized enzyme
assays.
Feel free to contact me for more information about these research projects. Currently there are openings for graduate assistants in my group. |